Tonight's UFC Fight Night card in Mexico City will go ahead without the middleweight matchup between Joe Pyfer and Kelvin Gastelum.

This month's UFC 313 pay-per-view served as a reminder that no bout is good to go until the cage door closes behind both athletes, with two fights falling through just hours before the card.

And the curse has struck again, this time in Mexico.

After both making weight and facing off on Friday, Joe Pyfer and Kelvin Gastelum will no longer throw down inside the Octagon after the former was struck down by illness.

The promotion announced the news Saturday, marking a sizable blow to the March 29 lineup at Arena CDMX.

It remains to be seen whether the UFC will reschedule the matchup for a later date. It was slated to serve as Gastelum's return to middleweight after a failed stint back at 170 pounds, which most recently saw his win over Daniel Rodriguez marred by a weight miss.

Pyfer, meanwhile, will have to wait to continue his momentum in the division. After falling short in his maiden main event against Jack Hermansson, "Bodybagz" bounced back emphatically by knocking out Marc-André Barriault last July.